Lasers Create Cancer Cure!

tumor

A substantial part of what makes cancer so deadly is that the tools we have to fight specific cancers work for some cases and don’t for others. That’s why despite numerous discoveries that promise cures for the disease, we just end up with a bunch of treatments and “therapeutic options.” Certain drugs work well against certain tumors and poorly against others. Treating cancer becomes a race to find effective treatment before the disease runs its final course.

Turns out microtubule (that I do my work on!) that help cells do things like divide and move actually might be able to extrapolate fairly accurate cancer prognoses and pathology. The proteins that make them up come in numerous forms called isotypes that differ minutely. Research indicates that different isotypes actually confer different cellular functions. For example, abundance of a particular isotype of beta-tubulin makes microtubules more dynamic and lends itself to taxane resistance in cancer cells.

Typical MALDI target

Typical MALDI target

Groundbreaking research by French researchers at Aix-Marseille Université may provide the next step in cancer treatment. Using matrix-assisted laser desorption/ionization time of flight mass spectroscopy (quite a mouthful! MALDI TOF Mass Spec for short), they found that tubulin, the protein subunit that builds microtubules, behaves unusually in the MALDI source. The result is that MALDI can detect and quantify tubulin isotypes.

E.g. isotypic distribution reading of peptide

E.g. isotypic distribution reading of peptide

Tubulin isotype analyses are expensive and time-consuming. MALDI may offer an effective screening tool for healthcare providers.

Source 1, 2, 3

Supeding

Pastry Chef (https://butterhub.org), software engineer (http://jamesding.org), and fitness enthusiast.

You may also like...

Leave a Reply

Read more:
Hookah: The Unbeknownst Silent Killer

It has been brought to my attention that for some reason, people are misled to think that hookah is a...

Risk Analysis: Cellphone radiation might do more than cause cancer!

There is plenty of literature and published work on the genetic toxicology (or lack thereof) of radiofrequency radiation, most findings are...

Concerning Ethnic Differences of Testosterone in Men

If you live in a diverse country, then you have probably noticed the variations in the body structure between ethnic...

Food you can eat a lot of without getting fat

Part of the feedback system for appetite include volume sensory neurons lining the stomach. Such receptors are activated by higher...

Close