Sleep deprivation increases brain sensitivity

rat

Busier folks lose a lot of sleep. Consequences include teary eyes, frequent yawning, and inattention during meetings or work. Apparently, not getting enough REM sleep also increases sensitivity to dopamine.

Tufic et al. published findings on depriving rats of sleep. Specifically, they deprived their stress groups of REM sleep by placing rats on relatively small, elevated platforms. They administered apomorphine, a dopamine agonist, to both stress groups and control groups and noted aggressive behavior, stereotyped behavior, verticalization, and body temperature. Apomorphine is an emetic (vomit-inducer) used to treat conditions including Parkinson’s disease and erectile dysfunction. William S. Burroughs advocated using apomorphine to treat heroine addiction.

Dopamine

Dopamine

They found that sleep deprivation is associated with sensitivity to apomorphine by all measures. Dopamine is postulated to modulate reward-learning and extraverted behavior. It might also account for the cocaine and methamphetamine addiction and ADHD. Since sleep deprivation might enhance dopamine-neuron sensitivity, not sleeping enough may account for adverse effects of dopamine-related drugs.

Source

Supeding

Pastry Chef (https://butterhub.org), software engineer (http://jamesding.org), and fitness enthusiast.

You may also like...

1 Response

  1. Dorothea Crayford says:

    There are many causes of sleep deprivation. The stresses of daily life may intrude upon our ability to sleep well, or perhaps we trade sleep for more work or play. We may have medical or mental-health conditions that disrupt our sleep, and be well aware that we are sleep-deprived.”^,*

    Please do look into our own web page <http://healthfitnessbook.com/

Leave a Reply

Read more:
Call to action: PhD level thinkers needed for healthcare transformation

It is without a doubt that the recent movement in big data will escalate to greater heights in years to...

Diagnosis of real-life Sherlock Holmes and artistic genius!

What does Sherlock Holmes do that's so extraordinary? He makes an astounding number of observations in a short time, pieces...

Optimize how much coffee you drink!

More frequently (especially after long flights) I find myself heading to the break room for a pick-me-up, but more and more...

Want to lose weight? Try sleeping more

A calorie deficit is hard to maintain (just ask anyone on the Atkins!), but more and more research is suggesting...

Close