Trans Fats — are we be wrong about them?


Trans fats have been so vilified that nutritional labels list how many grams of trans fats food contains. Whatever did they do to earn criminal status in the macronutrient world?

Chemistry students should recognize that “trans” refers to how the fatty acid chains are shaped; trans fats are zig-zagged. The terms “cis” and “trans” are applied to some bonds within fatty acid chains to differentiate the chains that curve like a U and those that curve like a Z. Most unsaturated fats that health-companies tout in their products are cis fats. In terms of physical properties, trans fatty acids and cis fatty acids are only marginally different; trans fats experience higher melting points since they’re more symmetrical but also lower boiling points. They show up a little differently on chemical analyses (e.g. exhibit different splitting in proton NMR).

Trans isomer

Trans isomer

Trans fats are unsaturated fatty acid chains, so they should pose less of a health concern than saturated fat. In terms of biology, it’s not entirely clear why trans fats are supposed to be bad. We know they are–scientific research indicates that trans fat consumption increases serum low-density lipoprotein (LDL) and decreases high-density lipoprotein (HDL) concentrations. Throwing off this ratio increases risk of heart and cardiovascular diseases.

Cis isomer

Cis isomer

Turns out, there may be more to the story than just trans vs cis. Studies in Canada funded by Alberta Livestock and Meat Agency and Dairy Farmers of Canada have shown that the trans fats naturally found in beef and dairy are actually beneficial to health. Specifically, vaccenic acid lowers total cholesterol levels while decreases LDL and triglyceride in the blood. However, due to the relative scarcity of such studies, public awareness towards trans fats has yet to be altered.

saturated unsaturated

A growing number of nutritionists and biologists propose that the problem isn’t trans fat; instead, health problems are the result of the chemical manufactured unsaturated fat. The chemical hydrogenation process used in industry often is incomplete and produces trans fats (in contrast enzymatic conversion produces cis fats). Some hypothesize that the partial hydrogenation of unsaturated fatty acids to trans fats constructs trans fats detrimental to health, though naturally produced trans fats do not have the same negative effects.

Source 1, 3, 4, 5, 6


Pastry Chef (, software engineer (, and fitness enthusiast.

You may also like...

3 Responses

  1. Kangster says:

    Why does it matter if a transfat is naturally or chemically produced as long as they have the same chemical structure? If they don’t, then what is wrong with chemically produced trans fats? plz explain

  2. Supeding says:

    thing is they don’t have the same chemical structure, not necessarily. There is a predictable pattern to synthetic hydrogenation in which carbons are isomerized from cis unsaturated to trans unsaturated. Thinking is maybe only specific trans fats are harmful (they happen to be the ones produced by chemical hydrogenation)

  1. May 7, 2013

    […] 5. […]

Leave a Reply

Read more:
Man vs Statistics! Survivor’s Guide to Eating Mushrooms

Note: this is not a guide to surviving. This is probability. Statistics is king. You find a gray mushroom and eat...

Laughing Gas – An Extensive Overview

Laughing gas, scientifically known as nitrous oxide (N2O), has been used as a sedation technique in many medical procedures. This...

Caffeine treats Parkinson’s disease, drink more coffee!

Epidemiology studies suggest show a correlation between caffeine intake and reduced risk for Parkinson's disease. Parkinson's usually presents with trembling,...

Sleep deprivation increases brain sensitivity

Busier folks lose a lot of sleep. Consequences include teary eyes, frequent yawning, and inattention during meetings or work. Apparently,...